Anti-inflammatory quinolizidine alkaloids from the aerial parts of Sophora tonkinensis

YY Zhang, D Liu, RR Ye, XQ Chen, RT Li… - Phytochemistry Letters, 2021 - Elsevier
alkaloids, including two new ones (1 and 2) (Fig. 1). Based on the traditional anti-inflammatory
efficacy of S. tonkinensis, the anti-inflammatory activities of all the isolates were evaluated …

Quinolizidine alkaloids from Sophora alopecuroides with anti-inflammatory and anti-tumor properties

JC Li, WF Dai, D Liu, ZJ Zhang, MY Jiang, KR Rao… - Bioorganic …, 2021 - Elsevier
quinolizidine alkaloids and flavonoids were principal constituents of this plant [3], [4], [5], [6],
[7], [8]. Specially, quinolizidine alkaloids … , cytisine-type and aloperine-type alkaloids [1], [2], [4…

Quinolizidine Alkaloids with Antiviral and Insecticidal Activities from the Seeds of Sophora tonkinensis Gagnep

J Zou, L Zhao, P Yi, Q An, L He, Y Li… - Journal of Agricultural …, 2020 - ACS Publications
quinolizidine alkaloids, including 11 undescribed ones, were obtained from the seeds of
S. tonkinensis… significant anti-TMV biological activities compared with the positive control …

Quinolizidine alkaloids from the roots of Sophora flavescens

JC Li, ZJ Zhang, D Liu, MY Jiang, RT Li… - Natural Product …, 2022 - Taylor & Francis
… of NO production may possess potential therapeutic role as anti-inflammatory agents.
Compounds 1–17 were evaluated for their inhibitory effect on NO production in LPS-stimulated …

Quinolizidine alkaloids derivatives from Sophora alopecuroides Linn: Bioactivities, structure-activity relationships and preliminary molecular mechanisms

Y Li, G Wang, J Liu, L Ouyang - European Journal of Medicinal Chemistry, 2020 - Elsevier
… Evidences have shown that SCA possessed peripheral and central analgesic characters
as well as anti-inflammatory activity on acute inflammatory processes [183]. Mechanistically, …

Five quinolizidine alkaloids with anti-tobacco mosaic virus activities from two species of Sophora

J Zhang, T Zhang, Q An, P Zhang, CY Tian… - Chinese Chemical …, 2024 - Elsevier
tonkinensis and the seeds of Sophora alopecuroides respectively. Notably, compound …
activities including antibacterial, anti-inflammatory, antiviral, anti-allergic, and antitumor activities […

Quinolizidine-type alkaloids: chemodiversity, occurrence, and bioactivity

W Cely-Veloza, MJ Kato, E Coy-Barrera - ACS omega, 2023 - ACS Publications
… cytotoxic, anti-inflammatory, and antianaphylactic activities. … , alkaloid 9 has been widely
studied for its anti-inflammatory … -Dou-Gen” (Sophora tonkinensis) were evaluated against the …

Four new quinolizidine alkaloids from the flowers of Sophora viciifolia

DD Gao, ZJ Zhang, HM Li, XQ Chen, D Liu, RT Li - Phytochemistry letters, 2020 - Elsevier
… pharmacological studies on Sophora have shown that quinolizidine alkaloids may against
… new quinolizidine alkaloids with anti-inflammatory and anti-influenza virus activities from the …

The biological activities of quinolizidine alkaloids

J Zhang, YQ Liu, J Fang - The Alkaloids: Chemistry and Biology, 2023 - Elsevier
… of Sophora flavescens (Kushen), Sophora tonkinensis, and … , the anti-inflammatory activity
of quinolizidine alkaloids is … and sophocarpine (35), and their derivatives in Sophora. The …

Five matrine-type alkaloids from Sophora tonkinensis

Q Tang, D Luo, DC Lin, WZ Wang, CJ Li… - Journal of natural …, 2021 - Springer
Sophora tonkinensis Gagnep., which belongs to the family of Leguminosae [1], and distributes
… Table 2 Anti-inflammatory activities of compounds 1–5 in LPS-stimulated RAW 264.7 cells …